منابع مشابه
Ontogeny of Myeloid Cells
Granulocytes, monocytes, macrophages, and dendritic cells (DCs) represent a subgroup of leukocytes, collectively called myeloid cells. During the embryonic development of mammalians, myelopoiesis occurs in a stepwise fashion that begins in the yolk sac and ends up in the bone marrow (BM). During this process, these early monocyte progenitors colonize various organs such as the brain, liver, ski...
متن کاملOntogeny of thymic NK1.1+ cells.
Thymic NK1.1+ cells are a recently described lymphocyte subset whose biologic function is not well defined. There is some controversy as to whether thymic NK1.1+ cells mature in a thymic or an extrathymic pathway. In this study, we examined the ontogeny of murine thymic NK1.1+ cells utilizing direct examination of freshly obtained fetal thymi as well as fetal thymi established in organ cultures...
متن کاملOntogeny and homeostasis of Langerhans cells.
Langerhans cells (LCs) refer to the dendritic cells (DCs) that populate the epidermis. Strategically located at one of the body's largest interfaces with the external environment, they form the first line of defense against pathogens that breach the skin. Although LCs share several phenotypical and functional features with lymphoid and non-lymphoid organ DCs, they also have unique properties th...
متن کاملOntogeny and Life Cycle of Dendritic Cells
D endritic cells (DC) are bone marrow-derived professional antigen-presenting cells (APC) which link innate and adaptive immune responses and which exhibit the exclusive ability of initiating primary immune responses by promoting the proliferation and polarisation of antigen-specific naïve T lymphocytes. This unique capacity derives from their high level of expression of MHC, co-stimulatory and...
متن کاملThe ontogeny of antigen-specific T cells
Although the fetal lamb is unable to form circulating antiovalbumin antibodies until about 120 days of gestation, ovalbumin-specific helper T cells can be stimulated to function at an earlier age. This would suggest that the critical event responsible for the precise sequential maturation of immunologic competence to different antigens at different developmental stages is not the first appearan...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1991
ISSN: 0085-2538
DOI: 10.1038/ki.1991.51